Can I Take More Than One Heartburn Medication?

Or can you increase the daily dose if one dose does not provide adequate relief?

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Can I Take More Than One Heartburn Medication?

Antacids (Mylanta®, Rolaids®) may be taken occasionally, if needed, while taking either an H2-blocker (Axid®, Pepcid® AC) or a PPI such as nonprescription omeprazole magnesium (Prilosec OTC).

If frequent antacid dosing is necessary, contact your physician.

You should not take an H2 blocker while taking a proton pump inhibitor (Prilosec®, Prilosec OTC®, Prevacid®, Prevacid 24 Hr.®, Zegerid OTC®, Nexium®) unless you are directed to do so by your physician.

Do not self-treat with two different H2 blockers at the same time or increase the daily dosage of any over-the-counter heartburn product above that which is recommended on the package label.


*Mylanta® is a registered trademark of Johnson & Johnson-Merck Consumer Pharmaceuticals Co. Rolaids® is a registered trademark of McNeil-PPC, Inc. Axid® is a registered trademark of GlaxoSmithKline, Inc. Pepcid® AC is a registered trademark of Johnson & Johnson-Merck Consumer Pharmaceuticals Co. Prevacid® and Prevacid&reg24HR are registered trademarks of TAP Pharmaceutical Products Inc. Zegerid OTC® is a registered trademark of Santarus, Inc. Nexium® is a registered trademark of AstraZeneca, LLC.


The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis or recommended treatments. OTC PPIs are only indicated for treatment of frequent heartburn. For severe heartburn or heartburn that persists after trying over-the-counter treatment or lifestyle modifications, visit your doctor to determine the right treatment for you. See the Terms and Conditions for more information.