For certain people with a genetic predisposition, prolonged and repeated acid reflux can damage the lining of the esophagus near where it joins the stomach. This condition is called Barrett’s esophagus and is linked to both gastroesophageal reflux disease (GERD) and inflammation of the esophagus (esophagitis).

Studies indicate that Barrett’s esophagus may put its sufferers at an increased risk of esophageal cancer. But even for people who have Barrett’s esophagus, the risk of getting cancer of the esophagus is small.

• 10% to 20% of the population experience frequent heartburn symptoms.
• About 10% of frequent heartburn sufferers develop Barrett’s esophagus.
• Fewer than 1% of people with Barrett’s esophagus will see that condition progress to cancer of the esophagus, with the highest incidence among white, middle-aged men.

Treating Barrett’s Esophagus

Currently, there is no known cure for Barrett’s esophagus, but the goal of treatment is to prevent further damage to the esophagus. To stop acid reflux from entering into the esophagus, medications such as H2 blockers or proton pump inhibitors (PPIs) are prescribed.

H2 blockers reduce acid production. Proton pump inhibitors are the most powerful inhibitors of acid production because they actually shut down the pumps that produce the acid.

Both kinds of medication have an excellent safety record and have been shown to improve symptoms, heal inflammation and prevent Barrett’s lining from getting worse. It is not known, however, if these treatments actually prevent cancer from occurring in people with Barrett’s esophagus. This is why it is so important for patients with this precancerous condition to have periodic screenings to spot any changes early.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis or recommended treatments. For severe heartburn or heartburn that persists after trying over-the-counter treatment or lifestyle modifications, visit your doctor to determine the right treatment for you. See the Terms and Conditions for more information.